The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 29, 2023

Filed:

Dec. 18, 2019
Applicant:

Lonza Walkersville, Inc., Walkersville, MD (US);

Inventors:

Bingnan Gu, Manvel, TX (US);

Caitlin M. Guenther, Houston, TX (US);

Anandita Seth, Sugar Land, TX (US);

Assignee:

LONZA WALKERVILLE, INC., Walkersville, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/86 (2006.01); C12N 15/113 (2010.01); C12N 15/864 (2006.01);
U.S. Cl.
CPC ...
C12N 15/86 (2013.01); C12N 15/113 (2013.01); C12N 15/8645 (2013.01); C12N 2710/10343 (2013.01); C12N 2830/008 (2013.01);
Abstract

The present disclosure relates to a mammalian cell line for producing adeno-associated virus (AAV), suitably including nucleic acids encoding helper genes and AAV genes, under the control of derepressible promoters. The disclosure also relates to isolated nucleic acid molecules that encode such genes, as well as methods of using the mammalian cells for producing AAVs.


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