The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 29, 2023
Filed:
Feb. 11, 2020
Genentech, Inc., South San Francisco, CA (US);
Yvonne M. Chen, San Mateo, CA (US);
Eugene Yu-Chuan Chiang, Menlo Park, CA (US);
Jane Louise Grogan, San Francisco, CA (US);
Simon-Peter Williams, Redwood City, CA (US);
Matthew Lawrence Albert, San Francisco, CA (US);
Genentech, Inc., South San Francisco, CA (US);
Abstract
Provided are anti-CD8 antibodies that bind human CD8 and do not stimulate or inhibit the activation of CD8T cells. Also provided are nucleic acids encoding such anti-CD8 antibodies, vectors comprising such nucleic acids, host cells comprising same, and methods of making such anti-CD8 antibodies. Also provided are anti-CD8 antibodies conjugated to a detectable label. Provided are methods of using such anti-CD8 antibodies to detect CD8T cells in a subject, monitor disease progress in a subject having cancer, and monitor treatment progress in a subject having cancer.