The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 29, 2023
Filed:
Mar. 09, 2022
Applicant:
Xencor, Inc., Monrovia, CA (US);
Inventors:
Matthew S. Faber, Glendora, CA (US);
Sung-Hyung Lee, San Gabriel, CA (US);
Yoon Kyung Kim, Pomona, CA (US);
Jing Qi, Arcadia, CA (US);
Kendra N. Avery, Hawthorne, CA (US);
Seung Y. Chu, Upland, CA (US);
Alex Nisthal, Monrovia, CA (US);
Matthew J. Bernett, Monrovia, CA (US);
John R. Desjarlais, Pasadena, CA (US);
Chad Borchert, Nowthen, MN (US);
Assignee:
Xencor, Inc., Pasadena, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61P 35/00 (2006.01); C07K 16/46 (2006.01); C12N 15/63 (2006.01);
U.S. Cl.
CPC ...
C07K 16/28 (2013.01); A61P 35/00 (2018.01); C07K 16/2809 (2013.01); C07K 16/468 (2013.01); C12N 15/63 (2013.01);
Abstract
Provided herein are novel CLDN6 binding domains, and anti-CLDN6×anti-CD3 antibodies that include such CLDN6 binding domains. Also provided herein are methods of using such antibodies for the treatment of CLDN6-associated cancers.