The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 29, 2023

Filed:

Feb. 22, 2022
Applicant:

Werewolf Therapeutics, Inc., Cambridge, MA (US);

Inventors:

William Winston, West Newton, MA (US);

Luke Evnin, San Francisco, CA (US);

Vinay Bhaskar, San Francisco, CA (US);

Giselle Knudsen, San Anselmo, CA (US);

Daniel J. Hicklin, Boston, MA (US);

Cynthia Seidel-Dugan, Belmont, MA (US);

Jose Andres Salmeron Garcia, Acton, MA (US);

Heather R. Brodkin, West Newton, MA (US);

Assignee:

Werewolf Therapeutics, Inc., Watertown, MA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 14/715 (2006.01); C07K 14/55 (2006.01); C07K 16/28 (2006.01); C07K 14/57 (2006.01); A61K 39/00 (2006.01); A61K 47/64 (2017.01); C07K 14/52 (2006.01);
U.S. Cl.
CPC ...
C07K 14/55 (2013.01); C07K 14/57 (2013.01); C07K 14/7155 (2013.01); C07K 16/2887 (2013.01); A61K 47/642 (2017.08); A61K 2039/505 (2013.01); C07K 14/52 (2013.01); C07K 2317/622 (2013.01); C07K 2317/73 (2013.01); C07K 2317/92 (2013.01); C07K 2319/02 (2013.01); C07K 2319/03 (2013.01); C07K 2319/30 (2013.01); C07K 2319/31 (2013.01); C07K 2319/33 (2013.01); C07K 2319/50 (2013.01); C07K 2319/70 (2013.01);
Abstract

Provided herein are separation moieties that are suitable for use in conjunction with a variety of therapeutic payloads. The separation moieties serve to generate conditionally active macromolecules whereby the macromolecules have reduced or minimal biological activity until the separation moieties are modified under specific conditions.


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