The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 29, 2023

Filed:

Jan. 25, 2019
Applicant:

Yale University, New Haven, CT (US);

Inventors:

Anna Pyle, Guilford, CT (US);

Olga Fedorova, Hamden, CT (US);

Erik Gunnar Jagdmann, Branford, CT (US);

Michael Van Zandt, Guilford, CT (US);

Lin Yuan, Guilford, CT (US);

Albert DeBerardinis, West Hartford, CT (US);

Assignee:

YALE UNIVERSITY, New Haven, CT (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 307/80 (2006.01); C07F 5/02 (2006.01); A61P 31/10 (2006.01); C07C 49/84 (2006.01); C07C 233/65 (2006.01); C07C 233/73 (2006.01); C07C 243/38 (2006.01); C07D 207/08 (2006.01); C07D 211/16 (2006.01); C07D 217/04 (2006.01); C07D 233/64 (2006.01); C07D 239/26 (2006.01); C07D 277/24 (2006.01); C07D 277/26 (2006.01); C07D 277/66 (2006.01); C07D 295/192 (2006.01); C07D 295/215 (2006.01); C07D 307/52 (2006.01); C07D 307/83 (2006.01); C07D 405/04 (2006.01); C07D 405/12 (2006.01); C07D 413/04 (2006.01);
U.S. Cl.
CPC ...
C07F 5/027 (2013.01); A61P 31/10 (2018.01); C07C 49/84 (2013.01); C07C 233/65 (2013.01); C07C 233/73 (2013.01); C07C 243/38 (2013.01); C07D 207/08 (2013.01); C07D 211/16 (2013.01); C07D 217/04 (2013.01); C07D 233/64 (2013.01); C07D 239/26 (2013.01); C07D 277/24 (2013.01); C07D 277/26 (2013.01); C07D 277/66 (2013.01); C07D 295/192 (2013.01); C07D 295/215 (2013.01); C07D 307/52 (2013.01); C07D 307/80 (2013.01); C07D 307/83 (2013.01); C07D 405/04 (2013.01); C07D 405/12 (2013.01); C07D 413/04 (2013.01);
Abstract

The present invention provides compositions and methods for inhibiting group II intron splicing for treating or preventing a disease or disorder associated with an organism harboring an active group II intron. The present invention also provides compositions and methods for inhibiting group II intron splicing for inhibiting, preventing or reducing growth of an organism harboring an active group II intron.


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