The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 29, 2023

Filed:

May. 05, 2021
Applicants:

Nurix Therapeutics, Inc., San Francisco, CA (US);

Gilead Sciences, Inc., Foster City, CA (US);

Inventors:

Hunter P. Shunatona, San Francisco, CA (US);

Galen Paul Shearn-Nance, San Francisco, CA (US);

Scott A. Mitchell, Foster City, CA (US);

John Buell, San Francisco, CA (US);

Assignees:

Nurix Therapeutics, Inc., San Francisco, CA (US);

Gilead Sciences, Inc., Foster City, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 519/00 (2006.01); C07D 471/04 (2006.01); C07D 487/14 (2006.01); C07D 471/10 (2006.01); A61P 31/12 (2006.01); A61P 35/00 (2006.01); A61P 37/02 (2006.01); A61P 31/18 (2006.01); A61P 31/20 (2006.01); A61K 31/4545 (2006.01); A61K 47/55 (2017.01);
U.S. Cl.
CPC ...
C07D 519/00 (2013.01);
Abstract

The present disclosure provides bifunctional compounds as HPK1 degraders via ubiquitin proteosome pathway, and method for treating diseases modulated by HPK1.


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