The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 29, 2023

Filed:

Jul. 22, 2019
Applicant:

Revolution Medicines, Inc., Redwood City, CA (US);

Inventors:

Brian R. Blank, Redwood City, CA (US);

Jennifer Pitzen, Redwood City, CA (US);

Gang Wang, Redwood City, CA (US);

Walter S. Won, Redwood City, CA (US);

Christos Tzitzilonis, Redwood City, CA (US);

Jie Jack Li, Redwood City, CA (US);

Elena S. Koltun, Redwood City, CA (US);

Naing Aay, Redwood City, CA (US);

Andreas Buckl, Redwood City, CA (US);

Kevin Mellem, Redwood City, CA (US);

Christopher Semko, Redwood City, CA (US);

Ash Jogalekar, Redwood City, CA (US);

Gert Kiss, Redwood City, CA (US);

Adrian Gill, Redwood City, CA (US);

Assignee:

REVOLUTION MEDICINES, INC., Redwood City, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4985 (2006.01); C07D 487/04 (2006.01); C07D 471/04 (2006.01); C07D 513/04 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); C07D 471/04 (2013.01); C07D 513/04 (2013.01); C07D 519/00 (2013.01);
Abstract

The present disclosure is directed to compounds of Formula IV: as inhibitors of SHP2 and their use in the treatment of diseases associated with SHP2. Also disclosed are pharmaceutical compositions comprising the same.


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