The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 29, 2023
Filed:
Oct. 07, 2021
Athenex, Inc., Buffalo, NY (US);
Sameer Urgaonkar, Williamsville, NY (US);
Ahmed M. Said, Williamsville, NY (US);
Nader N. Nasief Abdel Sayed, Amherst, NY (US);
Laura Beth Pitzonka, Blasdell, NY (US);
Murray John Cutler, Markham, CA;
Michael P. Smolinski, Amherst, NY (US);
Johnson Yiu-Nam Lau, Houston, TX (US);
Athenex, Inc., Buffalo, NY (US);
Abstract
The present disclosure relates to compounds of Formula (IA) and to their prodrugs, pharmaceutically acceptable salts, pharmaceutical compositions, methods of use, and methods for their preparation. The compounds disclosed herein are useful for the treatment of disorders in which P-glycoprotein and/or cytochrome P450 (e.g. CYP3A4) is modulated (e.g., cancers which have developed multi-drug resistance).