The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 29, 2023

Filed:

Jul. 09, 2019
Applicants:

Abivax, Paris, FR;

Centre National DE LA Recherche Scientifique, Paris, FR;

Universite DE Montpellier, Montpellier, FR;

Institut Curie, Paris, FR;

Inventors:

Didier Scherrer, Castelnau-le-Lez, FR;

Jamal Tazi, Clapiers, FR;

Florence Mahuteau-Betzer, Saint Remy-les-Chevreuse, FR;

Romain Najman, L'Hay-les-Roses, FR;

Julien Santo, Grabels, FR;

Cécile Apolit, Grabels, FR;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/12 (2006.01); C07C 237/40 (2006.01); C07C 255/50 (2006.01); C07C 311/16 (2006.01); C07D 205/04 (2006.01); C07D 213/74 (2006.01); C07D 213/81 (2006.01); C07D 405/12 (2006.01); C07D 413/12 (2006.01); C07F 7/18 (2006.01); A61P 31/12 (2006.01); C07C 233/65 (2006.01); C07D 213/38 (2006.01); C07D 213/75 (2006.01); C07D 239/42 (2006.01); C07D 241/12 (2006.01); C07D 239/16 (2006.01); C07D 239/22 (2006.01); C07D 403/12 (2006.01);
U.S. Cl.
CPC ...
C07D 401/12 (2013.01); A61P 31/12 (2018.01); C07C 233/65 (2013.01); C07C 237/40 (2013.01); C07C 255/50 (2013.01); C07C 311/16 (2013.01); C07D 205/04 (2013.01); C07D 213/38 (2013.01); C07D 213/74 (2013.01); C07D 213/75 (2013.01); C07D 213/81 (2013.01); C07D 239/16 (2013.01); C07D 239/22 (2013.01); C07D 239/42 (2013.01); C07D 241/12 (2013.01); C07D 403/12 (2013.01); C07D 405/12 (2013.01); C07D 413/12 (2013.01); C07F 7/1804 (2013.01);
Abstract

A compound: wherein Xrepresents an alkenylene group, a —NH—CO— group, a —CO—NH— group, Yrepresents an aryl group selected from pyridyl, pyrazinyl or pyrimidinyl, Xrepresents —O—, —CO—NH—, —NH—CO—NH—, —OCH—, —NH—CO—, a divalent 5-membered heteroaromatic ring comprising 1 to 4 heteroatoms or —SO—NH—, and Yrepresents a hydrogen atom, a hydroxyl group, a morpholinyl group, a piperidinyl group, optionally substituted by a (C-C)alkyl group, a piperazinyl group, optionally substituted by a (C-C)alkyl group, or —CRRRor alternatively X—Yrepresents —CONRR, wherein Rand Rform, together with the nitrogen atom a heterocyclic ring, optionally substituted by one or two (C-C)alkyl group, by a cyclopentyl group thus forming a spirocyclopentyl, or by a trifluoromethyl group, or any of its pharmaceutically acceptable salt, for use in the treatment and/or prevention of a RNA virus infection caused by a RNA virus belonging to group IV or V of the Baltimore classification.


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