The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 29, 2023

Filed:

Aug. 09, 2019
Applicant:

The Penn State Research Foundation, University Park, PA (US);

Inventors:

Jian Yang, State College, PA (US);

Chuying Ma, State College, PA (US);

Assignee:

The Penn State Research Foundation, University Park, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C08G 63/692 (2006.01); A61K 35/28 (2015.01); A61K 31/225 (2006.01); A61K 31/197 (2006.01); A61K 31/661 (2006.01); A61K 33/42 (2006.01); A61K 33/06 (2006.01); A61K 35/32 (2015.01); C08G 18/00 (2006.01); A61K 31/194 (2006.01); A61K 31/80 (2006.01); C08G 18/66 (2006.01); C08G 18/28 (2006.01); C08G 18/64 (2006.01);
U.S. Cl.
CPC ...
A61K 31/80 (2013.01); C08G 18/28 (2013.01); C08G 18/66 (2013.01); C08G 63/6924 (2013.01); C08G 18/64 (2013.01);
Abstract

This invention relates to compositions and methods for promoting and/or accelerating bone regeneration, repair, and/or healing and, in particular, to compositions and methods of promoting bone regeneration, growth, repair, and/or healing using graft or scaffold materials. In exemplary embodiments, the disclosed compositions may be used to promote and/or accelerate bone regeneration by delivering a composition to a bone site, the composition comprising (a) a citrate component, (b) a phosphate component, and, optionally, (c) a particulate inorganic material. The citrate component and/or phosphate component is advantageously released from the composition at the bone site. The released citrate component may function to increase alkaline phosphatase activity and/or expression at the bone site, and the increased alkaline phosphatase activity and/or expression may release the phosphate component. The composition may be delivered in various forms, e.g., as a biodegradable scaffold.


Find Patent Forward Citations

Yang, Jian. (2023). Compositions and methods for promoting bone regeneration (U.S. Patent No. 11738042). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11738042

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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