The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 22, 2023

Filed:

Apr. 02, 2021
Applicant:

Cardea Bio, Inc., San Diego, CA (US);

Inventors:

Pieter van Rooyen, La Jolla, CA (US);

Mitchell Lerner, La Jolla, CA (US);

Paul Hoffman, La Jolla, CA (US);

Brett R. Goldsmith, San Diego, CA (US);

Assignee:

Cardea Bio, Inc., San Diego, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
H01L 29/16 (2006.01); C12Q 1/6869 (2018.01); C12Q 1/6874 (2018.01); G01N 27/414 (2006.01); B01L 3/00 (2006.01); H01L 27/085 (2006.01); H01L 29/24 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6869 (2013.01); B01L 3/502715 (2013.01); B01L 3/502761 (2013.01); C12Q 1/6874 (2013.01); G01N 27/414 (2013.01); G01N 27/4145 (2013.01); G01N 27/4146 (2013.01); G01N 27/4148 (2013.01); H01L 27/085 (2013.01); H01L 29/1606 (2013.01); H01L 29/24 (2013.01); B01L 2300/0627 (2013.01); B01L 2300/0858 (2013.01); B01L 2300/0887 (2013.01); B01L 2300/12 (2013.01);
Abstract

An apparatus includes a biosensor integrated circuit (IC) chip having multiple well structures configured to receive a liquid comprising one or more biological analytes. The well structures include a passivation layer with an opening over one or more field effect transistors (gFETs) which include a layer of 2D channel material selected from molybdenum disulfide (MoS) and graphene; a drain electrode connected to a first end of the channel; a source electrode connected to a second end of the channel, wherein the individual gFETs are configured such that liquid received by the well structure is confined to form a liquid gate above a top surface of the channel. A system and method perform various functions of the apparatus.


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