The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 22, 2023
Filed:
May. 16, 2022
Applicant:
Nanjing Haohe Biotechnology Co., Ltd., Nanjing, CN;
Assignee:
Other;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 7/46 (2006.01); C12N 1/14 (2006.01); C12N 15/80 (2006.01); C12R 1/685 (2006.01);
U.S. Cl.
CPC ...
C12P 7/46 (2013.01); C12N 1/145 (2021.05); C12N 15/80 (2013.01); C12N 2800/10 (2013.01); C12R 2001/685 (2021.05);
Abstract
The disclosure discloses anengineered strain for reducing byproduct fumaric acid in a fermentation process of L-malic acid. Theengineered strain is anengineered strain in which a fumarate hydratase gene fum is knocked out. The disclosure overcomes the defects in the prior art, in the current process of producing malic acid through fermentation of, byproduct fumaric acid can be accumulated with the generation of malic acid so as to cause the improved cost of the subsequent malic acid purification process. The disclosure provides anengineered strain in which a fum gene is knocked out and a method for greatly reducing byproduct fumaric acid in the fermentation production of