The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 22, 2023
Filed:
Aug. 17, 2020
Applicant:
The Trustees of the University of Pennsylvania, Philadelphia, PA (US);
Inventors:
Lili Wang, Phoenixville, PA (US);
James M. Wilson, Philadelphia, PA (US);
Assignee:
The Trustees of the University of Pennsylvania, Philadelphia, PA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); A61P 1/00 (2006.01); A61P 1/16 (2006.01); A61P 3/00 (2006.01); A61P 43/00 (2006.01); A61P 25/28 (2006.01); C12N 15/00 (2006.01); C12N 15/79 (2006.01); C12N 15/86 (2006.01); C12N 9/00 (2006.01); C12N 9/10 (2006.01);
U.S. Cl.
CPC ...
C12N 9/1018 (2013.01); A61K 48/0058 (2013.01); C12N 15/86 (2013.01); C12Y 201/03003 (2013.01); C12N 2710/10343 (2013.01); C12N 2740/15043 (2013.01); C12N 2750/14032 (2013.01); C12N 2750/14033 (2013.01); C12N 2750/14043 (2013.01); C12N 2750/14071 (2013.01); C12N 2750/14143 (2013.01); C12N 2800/22 (2013.01);
Abstract
Viral vectors comprising engineered hOTC DNA and RNA sequences are provided which when delivered to a subject in need thereof are useful for treating hyperammonemia, ornithine transcarbamylase deficiency and symptoms associated therewith. Also provided are methods of using hOTC for treatment of liver fibrosis and/or cirrhosis in OTCD patients by administering hOTC.
Wang, Lili. (2023). Compositions useful in treatment of ornithine transcarbamylase (otc) deficiency (U.S. Patent No. 11732246). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11732246
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile