The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 22, 2023
Filed:
Sep. 16, 2020
Applicant:
Figene, Llc, Houston, TX (US);
Inventors:
Pete O'Heeron, Houston, TX (US);
Thomas Ichim, San Diego, CA (US);
Assignee:
Figene, LLC, Houston, TX (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/077 (2010.01); A61K 35/15 (2015.01); A61K 35/33 (2015.01); C12N 5/0784 (2010.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0656 (2013.01); A61K 35/15 (2013.01); A61K 35/33 (2013.01); C12N 5/0639 (2013.01); A61K 9/0019 (2013.01); A61K 9/0053 (2013.01); C12N 2501/10 (2013.01); C12N 2501/599 (2013.01);
Abstract
In some aspects, disclosed are methods and compositions for disc regeneration and/or repair using one or more components from conditioned media from fibroblasts. In certain cases, conditioned media is obtained from fibroblasts stimulated with one or more opioid receptor antagonists and one or more toll-like receptor agonists. Conditioned media from fibroblasts may be provided in an effective amount to an individual in need thereof.