The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 22, 2023
Filed:
Oct. 10, 2018
Applicants:
Yuntao Wu, Manassas, VA (US);
Hong Shang, Shenyang, CN;
Inventors:
Yuntao Wu, Manassas, VA (US);
Hong Shang, Shenyang, CN;
Assignee:
Other;
Primary Examiner:
Int. Cl.
CPC ...
A61P 31/18 (2006.01); C07K 16/28 (2006.01); A61K 47/68 (2017.01); A61K 38/17 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2806 (2013.01); A61K 38/1709 (2013.01); A61K 47/6811 (2017.08); A61P 31/18 (2018.01); C07K 2317/24 (2013.01); C07K 2317/75 (2013.01); C07K 2319/30 (2013.01);
Abstract
The present disclosure relates to composition and methodology for using the CD2 receptor to block viral replication, such as HIV-1 infection. In one embodiment, viral target cells such as blood CD4 T cells can be rendered resistant to HIV through stimulation of the CD2 receptor with either an antibody, a ligand, or a small molecule that binds to the CD2 receptor. Pre-stimulation of CD2 can be used to enhance the anti-HIV immunity and used to promote immune response from HIV infection or from an anti-HIV vaccine.