The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 22, 2023
Filed:
Jul. 10, 2020
Applicant:
Oasis Pharmaceuticals, Llc, Lexington, MA (US);
Inventor:
Richard J. Looby, Reading, MA (US);
Assignee:
Oasis Pharmaceuticals, LLC, Lexington, MA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); C07K 14/72 (2006.01); C07K 14/705 (2006.01);
U.S. Cl.
CPC ...
C07K 14/723 (2013.01); C07K 14/705 (2013.01); A61K 38/00 (2013.01);
Abstract
Provided herein are peptides comprising a mutated fragment of a wild-type protease-activated receptor-2 (PAR2). The peptides comprising a hydrophobic moiety can penetrate the cell membrane and act as an antagonist of PAR2. Also provided herein are compositions and cells comprising the peptides and methods of using the peptides.