The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 22, 2023

Filed:

Nov. 10, 2021
Applicants:

University of Washington, Seattle, WA (US);

Institute for Research IN Biomedicine, Bellinzona, CH;

Inventors:

Neil P. King, Seattle, WA (US);

David Baker, Seattle, WA (US);

Brooke Fiala, Seattle, WA (US);

Lance Joseph Stewart, Seattle, WA (US);

Laurent Perez, Bellinzona, CH;

Antonio Lanzavecchia, Bellinzona, CH;

Jessica Marcandalli, Bellinzona, CH;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 7/00 (2006.01); C12N 1/15 (2006.01); C12N 15/45 (2006.01); A61K 39/12 (2006.01); A61K 39/155 (2006.01); C07K 14/005 (2006.01); A61P 31/14 (2006.01); B82Y 5/00 (2011.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/005 (2013.01); A61K 39/12 (2013.01); A61P 31/14 (2018.01); B82Y 5/00 (2013.01); C12N 7/00 (2013.01); A61K 2039/575 (2013.01); C07K 2319/735 (2013.01); C12N 2760/18022 (2013.01); C12N 2760/18322 (2013.01); C12N 2760/18522 (2013.01);
Abstract

Disclosed herein are nanostructures and their use, where the nanostructures include (a) a plurality of first assemblies, each first assembly comprising a plurality of identical first polypeptides; (b) a plurality of second assemblies, each second assembly comprising a plurality of identical second polypeptides, wherein the second polypeptide differs from the first polypeptide; wherein the plurality of first assemblies non-covalently interact with the plurality of second assemblies to form a nanostructures; and wherein the nanostructure displays multiple copies of one or more paramyxovirus and/or pneumovirus F proteins or antigenic fragments thereof, on an exterior of the nanostructure.


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