The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 22, 2023
Filed:
Apr. 27, 2017
Applicant:
The Regents of the University of California, Oakland, CA (US);
Inventors:
Timothy J. Deming, Los Angeles, CA (US);
Eric G. Gharakhanian, Los Angeles, CA (US);
Assignee:
The Regents of the University of California, Oakland, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07K 7/06 (2006.01); C07K 14/00 (2006.01); C08G 69/10 (2006.01); C07K 1/113 (2006.01); C07K 1/107 (2006.01); C07K 1/00 (2006.01); C08G 69/48 (2006.01);
U.S. Cl.
CPC ...
C07K 7/06 (2013.01); C07K 1/006 (2013.01); C07K 1/107 (2013.01); C07K 1/113 (2013.01); C07K 1/1133 (2013.01); C07K 14/001 (2013.01); C08G 69/10 (2013.01); C08G 69/48 (2013.01);
Abstract
Methodology was developed for transformation of methionine residues into homocysteine derivatives. Methionine residues can undergo alkylation reactions at low pH to yield sulfonium ions, which can then be selectively demethylated to give alkyl homocysteine residues. This process tolerates many functional groups.