The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 22, 2023

Filed:

Aug. 12, 2020
Applicants:

Rutgers, the State University of New Jersey, New Brunswick, NJ (US);

Lehigh University, Bethlehem, PA (US);

Inventors:

Jeffrey D. Laskin, Piscataway, NJ (US);

Diane E. Heck, Rumson, NJ (US);

Carl J. Lacey, New Tripoli, PA (US);

Ned D. Heindel, Easton, PA (US);

Sherri C. Young, Bloomsbury, NJ (US);

Assignees:

LEHIGH UNIVERSITY, Bethlehem, PA (US);

RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY, New Brunswick, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07F 7/08 (2006.01); A61K 31/405 (2006.01); A61K 31/196 (2006.01); A61K 31/19 (2006.01); A61K 47/55 (2017.01); A61K 9/00 (2006.01); A61K 31/192 (2006.01); C07C 69/96 (2006.01); C07C 229/42 (2006.01); C07D 209/28 (2006.01); A61K 47/54 (2017.01);
U.S. Cl.
CPC ...
C07F 7/0812 (2013.01); A61K 9/0014 (2013.01); A61K 31/19 (2013.01); A61K 31/192 (2013.01); A61K 31/196 (2013.01); A61K 31/405 (2013.01); A61K 47/54 (2017.08); A61K 47/55 (2017.08); C07C 69/96 (2013.01); C07C 229/42 (2013.01); C07D 209/28 (2013.01); C07F 7/081 (2013.01); C07C 2602/10 (2017.05);
Abstract

Augmented or synergized anti-inflammatory constructs are disclosed including anti-inflammatory terpenes and/or vanilloids covalently conjugated to one another so that the activity of the conjugate is greater than the sum of its parts. Also disclosed are methods of improving the potency of an anti-inflammatory terpene or vanilloid by linking it to another anti-inflammatory terpene or vanilloid via a carbamate linkage, where the potency of the conjugate is greater than the sum of its parts.


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