The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 22, 2023
Filed:
Oct. 19, 2018
Francois Lepine, Lavaltrie, CA;
The General Hospital Corporation, Boston, MA (US);
Aptuit (Verona) Srl, an Evotec Company, Verona, IT;
Laurence Rahme, Brookline, MA (US);
Francois Lepine, Lavaltrie, CA;
Damien Maura, Somerville, MA (US);
Carmela Napolitano, Verona, IT;
Antonio Felici, Vigasio, IT;
Michele Negri, Zevio, IT;
Stefano Fontana, Pove del Grappa, IT;
Daniele Andreotti, San Giovanni Lupatoto, IT;
The General Hospital Corporation, Boston, MA (US);
Aptuit (Verona) SRL, An Evotec Company, Verona, IT;
Abstract
The present application provides malonamide compounds, and derivatives thereof (e.g., N-aryl malonamides (NAM), acetamides, oxalamides, and the like), that are useful, for example, for the treatment of acute, chronic/persistent, and/or relapsing infections. Pharmaceutical compositions, methods of treating diseases (e.g., bacterial infections), and methods of reducing bacterial virulence are also provided.