The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 22, 2023
Filed:
Aug. 03, 2018
Osaka University, Suita, JP;
Yoshifumi Shirakami, Suita, JP;
Hayato Ikeda, Suita, JP;
Yasukazu Kanai, Suita, JP;
Eku Shimosegawa, Suita, JP;
Jun Hatazawa, Suita, JP;
Tadashi Watabe, Suita, JP;
Kazuko Kaneda, Suita, JP;
OSAKA UNIVERSITY, Suita, JP;
Abstract
The invention relates to a method of producing the radiolabeled aryl compound (I) Ar—X, or a salt thereof, wherein X isAt,At,I,I,I, orI. The method involves reacting the aryl boronic acid compound (II) Ar—Y, or a salt thereof, wherein Y is a borono group (—B(OH)) or an ester group thereof, with a radionuclide selected fromAt,At,I,I,I andI, in the presence of an oxidizing agent selected from an alkali metal iodide, an alkali metal bromide, N-bromosuccinimide, N-chlorosuccinimide and hydrogen peroxide, in water.