The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 22, 2023

Filed:

Jan. 07, 2019
Applicant:

Sernova Corporation, London, CA;

Inventors:

Craig Hasilo, Montreal, CA;

Justin Leushner, London, CA;

Daniel Nicholas Haworth, Marlborough, GB;

Simon Shohet, Potton, GB;

Philip Michael Toleikis, Vancouver, CA;

Delfina Maria Mazzuca Siroen, London, CA;

Assignee:

Sernova Corporation, London, CA;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61L 27/38 (2006.01); A61L 27/16 (2006.01); C12N 5/071 (2010.01); A61F 2/02 (2006.01); A61L 27/56 (2006.01); A61L 27/54 (2006.01); A61L 27/58 (2006.01); A61M 39/02 (2006.01); A61K 35/12 (2015.01);
U.S. Cl.
CPC ...
A61L 27/3886 (2013.01); A61F 2/022 (2013.01); A61L 27/16 (2013.01); A61L 27/3804 (2013.01); A61L 27/3834 (2013.01); A61L 27/54 (2013.01); A61L 27/56 (2013.01); A61L 27/58 (2013.01); A61M 39/0247 (2013.01); C12N 5/0677 (2013.01); A61K 35/12 (2013.01); A61L 2300/64 (2013.01); A61L 2400/18 (2013.01); A61L 2420/00 (2013.01); A61M 2039/0282 (2013.01); C12N 2533/30 (2013.01);
Abstract

Devices and methods for transplanting cells in a host body are described. The cell comprises a porous scaffold that allows ingrowth of vascular and connective tissues, a plug or plug system configured for placement within the porous scaffold, and a seal configured to enclose a proximal opening in the porous scaffold. The device may further comprise a cell delivery device for delivering cells into the porous scaffold. The method of cell transplantation comprises a two step process. The device is incubated in the host body to form a vascularized collagen matrix around a plug positioned within the porous scaffold. The plug is then retracted from the porous scaffold, and cells are delivered into the vascularized space created within the porous scaffold.


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