The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 22, 2023

Filed:

Sep. 02, 2020
Applicant:

Valo Therapeutics Oy, Helsinki, FI;

Inventors:

Vincenzo Cerullo, Helsinki, FI;

Markus Vähä-Koskela, Helsinki, FI;

Mari Hirvinen, Helsinki, FI;

Cristian Capasso, Helsinki, FI;

Assignee:

Valo Therapeutics Oy, Helsinki, FI;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/385 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/0011 (2013.01); A61K 2039/522 (2013.01); A61K 2039/525 (2013.01); A61K 2039/60 (2013.01); C12N 2710/10042 (2013.01);
Abstract

The present invention relates to adenoviral vectors, wherein the viral capsid has been coated with polypeptides, which are capable of stimulating a peptide-specific immune response in a subject and uses thereof. Furthermore, the present invention relates to methods of treating diseases, e.g. cancer, by adenoviral vectors which have been coated by polypeptides causing peptide-specific immune response. Also the present invention relates to a method of coating adenoviral vectors by specific peptides as well as to a method of identifying those peptides suitable for coating the capsid of an adenoviral vector.


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