The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 22, 2023
Filed:
Feb. 17, 2021
Applicant:
University of Kentucky Research Foundation, Lexington, KY (US);
Inventors:
Vivek M. Rangnekar, Nicholasville, KY (US);
Ravshan Burikhanov, Lexington, KY (US);
David S. Watt, Lexington, KY (US);
Assignee:
University of Kentucky Research Foundation, Lexington, KY (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/7048 (2006.01); A61K 45/06 (2006.01); A61K 31/4706 (2006.01); A61K 31/704 (2006.01); A61K 31/55 (2006.01); A61K 31/4545 (2006.01); A61K 31/675 (2006.01); A61K 31/497 (2006.01); A61K 31/517 (2006.01); A61K 31/4745 (2006.01);
U.S. Cl.
CPC ...
A61K 31/7048 (2013.01); A61K 31/4545 (2013.01); A61K 31/4706 (2013.01); A61K 31/4745 (2013.01); A61K 31/497 (2013.01); A61K 31/517 (2013.01); A61K 31/55 (2013.01); A61K 31/675 (2013.01); A61K 31/704 (2013.01); A61K 45/06 (2013.01);
Abstract
A method of treating cancer in an individual includes a step of administering to the individual a pharmaceutically effective amount of (a) a first active agent adapted for producing secretion of prostate apoptosis response-4 (Par-4) from normal cells and (b) a second active agent adapted for elevating GRP78 receptors for Par-4 on a surface of a cancer cell in the individual.