The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 22, 2023
Filed:
Jul. 13, 2021
The Board of Regents for the Oklahoma Agricultural and Mechanical Colleges, Stillwater, OK (US);
Toby Larue Nelson, Stillwater, OK (US);
Santosh Adhikari, Los Alamos, NM (US);
Erika Lutter, Stillwater, OK (US);
Karen Wozniak, Guthrie, OK (US);
The Board of Regents for the Oklahoma Agricultural and Mechanical Colleges, Stillwater, OK (US);
Abstract
Herein, is taught a Eumelanin-inspired antimicrobial capable of overcoming methicillin resistant(MSRA) and. By ligating quaternary ammonium functionalized 'arms' on to a Eumelanin-inspired indole, with intrinsic antimicrobial activity, a cell wall destroying antimicrobial agent was prepared. It also has antifungal effects against. Further, Eumelanin-inspired phenyleneethynylene (EIPE) derivatives EIPE-1 and EIPE-HCl are novel compounds. EIPE structure serves as scaffolding for functional groups that may have antibacterial properties. Both gram-positive and gram-negative organisms are screened against EIPE derivatives using a standardized Kirby Bauer disk agar diffusion assay. These results showed that EIPE-1 has antibacterial properties against some pathogenic gram-positive organisms.