The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 22, 2023

Filed:

Sep. 23, 2022
Applicants:

Emory University, Atlanta, GA (US);

Georgia Tech Research Corporation, Atlanta, GA (US);

Chapman University, Orange, CA (US);

Children's Healthcare of Atlanta, Inc., Atlanta, GA (US);

Inventors:

Wilbur A. Lam, Decatur, GA (US);

Caroline Hansen, Atlanta, GA (US);

Yumiko Sakurai, Atlanta, GA (US);

Andrew Lyon, Irvine, GA (US);

Assignees:

Emory University, Atlanta, GA (US);

Georgia Tech Research Corporation, Atlanta, GA (US);

Chapman University, Orange, CA (US);

Children's Healthcare of Atlanta, Inc., Atlanta, GA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/50 (2006.01); A61K 38/37 (2006.01);
U.S. Cl.
CPC ...
A61K 9/5031 (2013.01); A61K 9/5036 (2013.01); A61K 9/5073 (2013.01); A61K 9/5089 (2013.01); A61K 38/37 (2013.01);
Abstract

This disclosure relates to microcapsule particles for targeted delivery of drugs. In certain embodiments, the particles comprise polyelectrolyte polymers, e.g., layers of anionic polymers and cationic polymers. In certain embodiments, the particles have a fibrinogen coating. In certain embodiments, the particles contain a polysaccharide core and/or a polysaccharide coating encapsulating drugs, proteins, clotting agents, coagulation factors, or anticoagulants. In certain embodiments, this disclosure contemplates methods of using particles disclosed herein to prevent or reduce onset of or duration of bleeding. In certain embodiments, this disclosure contemplates methods of using particles disclosed herein to prevent or reduce onset of blood clotting.


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