The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 22, 2023

Filed:

Jul. 18, 2019
Applicant:

Celltrion Inc., Incheon, KR;

Inventors:

So Young Kim, Incheon, KR;

Yeon Kyeong Shin, Incheon, KR;

Hye Young Kang, Incheon, KR;

Kwang Woo Kim, Incheon, KR;

Jun Seok Oh, Incheon, KR;

Su Jung Kim, Incheon, KR;

Joon Won Lee, Incheon, KR;

Won Yong Han, Incheon, KR;

Jae Bin Lee, Incheon, KR;

Ji Won Roh, Incheon, KR;

Ji Min Kwak, Incheon, KR;

Assignee:

CELLTRION INC., Incheon, KR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/08 (2006.01); A61K 9/19 (2006.01); A61K 47/02 (2006.01); A61K 47/10 (2017.01); A61K 47/12 (2006.01); A61K 47/18 (2017.01); A61K 47/26 (2006.01); C07K 16/32 (2006.01);
U.S. Cl.
CPC ...
A61K 9/08 (2013.01); A61K 9/19 (2013.01); A61K 47/02 (2013.01); A61K 47/10 (2013.01); A61K 47/12 (2013.01); A61K 47/183 (2013.01); A61K 47/26 (2013.01); C07K 16/32 (2013.01);
Abstract

A stable liquid pharmaceutical formulation according to the present invention includes an antibody or antigen-binding fragment thereof, a surfactant, a sugar or a sugar derivative, a buffer, and a stabilizer. The stable liquid pharmaceutical formulation according to the present invention has low viscosity not only when antibody content is low but also when antibody content is high, and exhibits superior long-term storage stability based on superior stability observed under accelerated conditions and harsh conditions.


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