The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 22, 2023

Filed:

Nov. 16, 2018
Applicant:

Swedish Orphan Biovitrum Ab (Publ), Stockholm, SE;

Inventor:

Jonas Fransson, Uppsala, SE;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61J 1/20 (2006.01); B01J 47/15 (2017.01); A61M 5/19 (2006.01); A61M 5/31 (2006.01); A61M 5/32 (2006.01);
U.S. Cl.
CPC ...
A61J 1/2003 (2015.05); A61M 5/19 (2013.01); A61M 5/3145 (2013.01); A61M 5/329 (2013.01); B01J 47/15 (2017.01); A61M 2005/3128 (2013.01); A61M 2205/02 (2013.01); A61M 2205/19 (2013.01);
Abstract

A pre-filled syringe is disclosed, comprising a barrel and a plunger, the barrel having an outlet, the barrel containing a pharmaceutically acceptable solution having a non-physiological pH, wherein the syringe further comprises an ion exchange material. The ion exchange material is provided at a position to allow contact with the pharmaceutically acceptable solution upon ejection of the pharmaceutically acceptable solution from the barrel via the outlet. The ion exchange material is capable of adjusting the pH of the solution from a non-physiological pH, at which the pharmaceutically acceptable solution is stored in order to ensure acceptable shelf life, to a more physiological pH at which the discomfort and/or pain experienced during injection may be alleviated.


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