The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 15, 2023

Filed:

Dec. 13, 2021
Applicant:

Tempus Labs, Inc., Chicago, IL (US);

Inventors:

Aïcha Bentaieb, Mountain View, CA (US);

Martin Christian Stumpe, Belmont, CA (US);

Aly Azeem Khan, Chicago, IL (US);

Assignee:

TEMPUS LABS, INC., Chicago, IL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G16C 20/70 (2019.01); G06V 20/69 (2022.01); G06V 10/774 (2022.01);
U.S. Cl.
CPC ...
G06V 10/7747 (2022.01); G06V 20/698 (2022.01); G16C 20/70 (2019.02);
Abstract

A system and method are provided for training and using a machine learning model to analyze hematoxylin and eosin (H&E) slide images, where the machine learning model is trained using a training data set comprising a plurality of unmarked H&E images and a plurality of marked H&E images, each marked H&E image being associated with one unmarked H&E image and each marked H&E image including a location of one or more molecules determined by analyzing a multiplex IHC image having at least two IHC stains, each IHC stain having a unique color and a unique target molecule. Predicted molecules and locations identified with the machine learning model result in an immunotherapy response class being assigned to the H&E slide image.


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