The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 15, 2023

Filed:

Sep. 25, 2020
Applicants:

The University of Kansas, Lawrence, KS (US);

Kansas State University Research Foundation, Manhattan, KS (US);

Inventors:

Peng Zhang, Gainesville, FL (US);

Yong Zeng, Gainesville, FL (US);

Mei He, Gainesville, FL (US);

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/543 (2006.01); B01L 3/00 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
G01N 33/54393 (2013.01); B01L 3/502707 (2013.01); B01L 3/502761 (2013.01); G01N 33/54326 (2013.01); G01N 33/54353 (2013.01); G01N 33/6872 (2013.01); B01L 2200/0631 (2013.01); B01L 2200/0647 (2013.01); B01L 2300/0636 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/0887 (2013.01);
Abstract

A graphene-based sandwich immunoassay for detecting whether a target biological substance is present in a sample, generally comprising contacting said sample with a plurality of particles coated with graphene nanosheets, each particle having at least one targeting receptor, such that the target biological substance, if present, associates with the targeting receptor, and detecting the presence of the target biological substance in the sample by subsequently contacting the sample with a detection antibody, wherein the detection antibody is capable of targeting and binding with the target biological substance if bound to the targeting receptor to yield a detectable complex. The targeting receptor can be an antibody or fragment thereof. The target biological substance can be an exosome.


Find Patent Forward Citations

Loading…