The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 15, 2023
Filed:
Mar. 03, 2020
Procella Therapeutics Ab, Tullinge, SE;
Chuen Yan Leung, Stockholm, SE;
Jonathan Clarke, Stockholm, SE;
Jiejia Xu, Solna, SE;
Federica Santoro, Stockholm, SE;
Makoto Sahara, Stockholm, SE;
Kenneth R. Chien, Cambridge, MA (US);
Procella Therapeutics AB, Tullinge, SE;
Abstract
The present invention provides genetic markers for identifying engraftable human cardiac ventricular progenitor cells. The engraftment markers of the invention include angiogenic markers and extracellular matrix markers. Human ventricular progenitor cells expressing these markers are capable of forming ventricular tissue in vivo that is vascularized and supported by an extracellular matrix. Methods of engrafting human cardiac ventricular progenitor cells by transplanting into a subject progenitor cells that express the engraftment markers are also provided.