The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 15, 2023

Filed:

Nov. 07, 2019
Applicant:

Lawrence Livermore National Security, Llc, Livermore, CA (US);

Inventors:

David Soscia, Livermore, CA (US);

Heather Ann Enright, Livermore, CA (US);

Nicholas Fischer, Livermore, CA (US);

Doris Mailie Lam, Dublin, CA (US);

Angela C. Tooker, Livermore, CA (US);

Michael Triplett, Livermore, CA (US);

Elizabeth K. Wheeler, Livermore, CA (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12M 1/32 (2006.01); C12N 5/00 (2006.01); C12M 1/42 (2006.01); B01L 3/00 (2006.01); G01N 27/30 (2006.01);
U.S. Cl.
CPC ...
C12M 23/12 (2013.01); B01L 3/5085 (2013.01); C12M 35/02 (2013.01); C12N 5/0068 (2013.01); G01N 27/30 (2013.01); B01L 2300/0829 (2013.01); C12N 2513/00 (2013.01); C12N 2539/00 (2013.01);
Abstract

The present disclosure relates to a biocompatible, in vitro probe system. The probe system may have a substrate and a culture well supported on the substrate. The culture well defines a three-dimensional volume for containing in vitro cultures of electroactive cells. The probe system has at least one probe subsystem supported on the substrate. The probe subsystem has at least one probe having an array of electrodes, with the probe being disposed within the culture well for in vitro electrically communicating with the electroactive cells. The probe subsystem is adapted to be interfaced to an external instrumentation/recording device.


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