The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 15, 2023
Filed:
Mar. 15, 2022
Bolt Threads, Inc., Emeryville, CA (US);
Joshua Kittleson, Pleasant Hill, CA (US);
Thomas Stevens, San Francisco, CA (US);
Rena Hill, Oakland, CA (US);
Carlos Gustavo Pesce, San Francisco, CA (US);
David N. Breslauer, San Francisco, CA (US);
Daniel M. Widmaier, San Francisco, CA (US);
BOLT THREADS, INC., Emeryville, CA (US);
Abstract
The present disclosure relates to methods for producing recombinant proteins, as well as compositions used in and produced by such methods. Specifically, the present disclosure relates to methods for producing high secreted yields of recombinant proteins, and the compositions provided herein include expression constructs, recombinant vectors, and recombinant host cells that comprise polynucleotide sequences encoding proteins operably linked to recombinant secretion signals that comprise the leader peptide of the α-mating factor (αMF) ofand a non-αMF signal peptide.