The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 15, 2023
Filed:
Oct. 17, 2019
Applicant:
Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing, CN;
Inventors:
Hailin Qin, Beijing, CN;
Lianqiu Wu, Beijing, CN;
Xiang Li, Beijing, CN;
Haijing Zhang, Beijing, CN;
Li Song, Beijing, CN;
Huachen Song, Beijing, CN;
Anjun Deng, Beijing, CN;
Xiaonan Tang, Beijing, CN;
Zhihui Zhang, Beijing, CN;
Xiang Li, Beijing, CN;
Zhihong Li, Beijing, CN;
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 455/03 (2006.01); A61P 31/04 (2006.01); A61P 29/00 (2006.01); A61P 1/04 (2006.01); A61P 31/10 (2006.01); A61P 35/00 (2006.01); C07D 493/14 (2006.01); C07D 493/22 (2006.01);
U.S. Cl.
CPC ...
C07D 455/03 (2013.01); A61P 1/04 (2018.01); A61P 29/00 (2018.01); A61P 31/04 (2018.01); A61P 31/10 (2018.01); A61P 35/00 (2018.01); C07D 493/14 (2013.01); C07D 493/22 (2013.01);
Abstract
An 8-dihalomethyl berberine-type quaternary ammonium salt compound represented by general formula (I) or (II) and an application thereof in preparing a drug. The compound shows hydrophilicity and has antimicrobial, anti-inflammatory, anti-ulcerative colitis, and antitumor activities, while having no or low toxicity.