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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11725006 B1

PDFFull Text
Date of Patent:
Aug. 15, 2023

Filed:

Oct. 17, 2019

Hydrophilic berberine-type derivative and application thereof in preparing drug

Applicant:

Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing, CN;

Inventors:

Hailin Qin, Beijing, CN;

Lianqiu Wu, Beijing, CN;

Xiang Li, Beijing, CN;

Haijing Zhang, Beijing, CN;

Li Song, Beijing, CN;

Huachen Song, Beijing, CN;

Anjun Deng, Beijing, CN;

Xiaonan Tang, Beijing, CN;

Zhihui Zhang, Beijing, CN;

Xiang Li, Beijing, CN;

Zhihong Li, Beijing, CN;

Assignee:

INSTITUTE OF MATERIA MEDIC, CHINESE ACADEMY OF MEDICAL SCIENCES, Beijing, CN;

Attorney:

Merchant & Gould P.C.

Primary Examiner:

Paul V Ward

Int. Cl.
CPC ...
C07D 455/03 (2006.01); A61P 31/04 (2006.01); A61P 29/00 (2006.01); A61P 1/04 (2006.01); A61P 31/10 (2006.01); A61P 35/00 (2006.01); C07D 493/14 (2006.01); C07D 493/22 (2006.01);
U.S. Cl.
CPC ...
C07D 455/03 (2013.01); A61P 1/04 (2018.01); A61P 29/00 (2018.01); A61P 31/04 (2018.01); A61P 31/10 (2018.01); A61P 35/00 (2018.01); C07D 493/14 (2013.01); C07D 493/22 (2013.01);
Abstract

An 8-dihalomethyl berberine-type quaternary ammonium salt compound represented by general formula (I) or (II) and an application thereof in preparing a drug. The compound shows hydrophilicity and has antimicrobial, anti-inflammatory, anti-ulcerative colitis, and antitumor activities, while having no or low toxicity.

Find Patent Forward Citations

Qin, Hailin. (2023). Hydrophilic berberine-type derivative and application thereof in preparing drug (U.S. Patent No. 11725006). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11725006

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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