The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 15, 2023
Filed:
Apr. 27, 2018
Applicants:
Fuso Pharmaceutical Industries, Ltd., Osaka, JP;
Ken-ichi Yamada, Fukuoka, JP;
Inventors:
Ken-ichi Yamada, Fukuoka, JP;
Tomomi Ide, Fukuoka, JP;
Yuma Ishida, Fukuoka, JP;
Go Ichien, Tokyo, JP;
Keiichi Yamamoto, Osaka, JP;
Assignees:
Other;
FUSO PHARMACEUTICAL INDUSTRIES, LTD., Osaka, JP;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 21/64 (2006.01); G01N 21/78 (2006.01); G01N 33/533 (2006.01); C07D 413/12 (2006.01); C07K 16/18 (2006.01);
U.S. Cl.
CPC ...
C07D 413/12 (2013.01); C07K 16/18 (2013.01); G01N 21/6428 (2013.01); G01N 21/78 (2013.01); G01N 33/533 (2013.01);
Abstract
A detection reagent for comprehensively detecting an oxidized state and a glycated state of a low-density lipoprotein. While an oxidized low-density lipoprotein and a glycated low-density lipoprotein are detected with a fluolophore-labelled antibody, a lipid radical is detected with a fluorescent nitroxide 2,2,6-trimethyl-4-(4-nitrobenzo[1,2,5]oxadiazol-7-ylamino)-6-pentylpiperadine-1-oxyl (NBD-Pen).