The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 15, 2023

Filed:

Jan. 07, 2022
Applicant:

Knopp Biosciences Llc, Pittsburgh, PA (US);

Inventors:

Michael E. Bozik, Wexford, PA (US);

Scott S. Harried, Sun Prairie, WI (US);

Lynn Resnick, Pittsburgh, PA (US);

George T. Topalov, Pittsburgh, PA (US);

Justin K. Belardi, Pittsburgh, PA (US);

Charles A. Flentge, Mars, PA (US);

David A. Mareska, Pittsburgh, PA (US);

James S. Hale, Pittsburgh, PA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4184 (2006.01); C07D 235/30 (2006.01); C07D 471/04 (2006.01); C07D 405/04 (2006.01);
U.S. Cl.
CPC ...
C07D 235/30 (2013.01); A61K 31/4184 (2013.01); C07D 405/04 (2013.01); C07D 471/04 (2013.01);
Abstract

Provided herein are optionally substituted benzoimidazol-1,2-yl amides, pharmaceutical compositions comprising a therapeutically effective amount of such compounds and a pharmaceutically acceptable excipient, and methods of treating Kv7 associated diseases, such as, epilepsy, amyotrophic lateral sclerosis, various types of pain, hyperexcitability, a dyskinesia, dystonia, mania and tinnitus with such compounds and pharmaceutical compositions.


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