The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 15, 2023

Filed:

Oct. 16, 2014
Applicants:

Sumitomo Chemical Company, Limited, Tokyo, JP;

Riken, Wako, JP;

Inventors:

Atsushi Kuwahara, Osaka, JP;

Yoshiki Sasai, Kobe, JP;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61L 27/38 (2006.01); A61K 35/545 (2015.01); C12N 5/079 (2010.01); A61K 35/30 (2015.01);
U.S. Cl.
CPC ...
A61L 27/3878 (2013.01); A61K 35/545 (2013.01); A61L 27/383 (2013.01); A61L 27/3834 (2013.01); A61L 27/3895 (2013.01); C12N 5/0621 (2013.01); A61K 35/30 (2013.01); A61L 2400/06 (2013.01); A61L 2430/16 (2013.01); C12N 2501/10 (2013.01); C12N 2501/11 (2013.01); C12N 2501/115 (2013.01); C12N 2501/155 (2013.01); C12N 2501/385 (2013.01); C12N 2501/41 (2013.01); C12N 2501/415 (2013.01); C12N 2501/727 (2013.01); C12N 2501/999 (2013.01); C12N 2506/02 (2013.01);
Abstract

The invention provides a method for producing a ciliary marginal zone stem cell induced to differentiate from a pluripotent stem cell, including either the following step (1) or step (2), or both of these steps: (1) a step of floating culturing cells obtained from a cell aggregate containing a ciliary marginal zone-like structure induced to differentiate from pluripotent stem cells, thereby obtaining a retinosphere; and (2) a step of collecting stage specific embryonic antigen-1 positive cells from cells obtained from a cell aggregate containing a ciliary marginal zone-like structure induced to differentiate from pluripotent stem cells.


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