The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 15, 2023
Filed:
Dec. 04, 2019
Applicants:
Jn Biosciences, Llc, Mountain View, CA (US);
Abmuno Therapeutics, Llc, Berkeley, CA (US);
Inventors:
J. Yun Tso, Menlo Park, CA (US);
Naoya Tsurushita, Palo Alto, CA (US);
Omar Duramad, Berkeley, CA (US);
Assignees:
JN Biosciences, LLC, Mountain View, CA (US);
Abmuno Therapeutics, LLC, Berkeley, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/28 (2006.01); A61K 39/085 (2006.01); A61K 39/08 (2006.01); A61K 39/39 (2006.01); C07K 16/30 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/39541 (2013.01); A61K 39/08 (2013.01); A61K 39/085 (2013.01); A61K 39/39 (2013.01); A61K 39/3955 (2013.01); C07K 16/2803 (2013.01); C07K 16/2809 (2013.01); C07K 16/2827 (2013.01); C07K 16/2878 (2013.01); C07K 16/2896 (2013.01); C07K 16/3061 (2013.01); A61K 2039/507 (2013.01); A61K 2039/545 (2013.01); A61K 2121/00 (2013.01); C07K 2317/24 (2013.01); C07K 2317/30 (2013.01); C07K 2317/33 (2013.01); C07K 2317/34 (2013.01); C07K 2317/70 (2013.01); C07K 2317/732 (2013.01); C07K 2317/734 (2013.01); C07K 2317/76 (2013.01); C07K 2317/90 (2013.01); C07K 2317/92 (2013.01); C07K 2317/94 (2013.01); Y02A 50/30 (2018.01);
Abstract
The invention provides monoclonal antibodies that specifically bind to TIGIT. The monoclonal antibodies have the capacity for substantial activation of T cells and natural killer cells by inhibiting binding of TIGIT to CD155. The monoclonal antibodies can be used for treatment of cancer and infectious disease, among other applications.