The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 15, 2023

Filed:

Dec. 10, 2021
Applicants:

Janssen Vaccines & Prevention B.v., Leiden, NL;

Bavarian Nordic, Kvistgaard, DK;

Inventors:

Frank Wegmann, Leiden, NL;

Johannes Petrus Maria Langedijk, Amsterdam, NL;

JerĂ´me Hubertina Henricus Victor Custers, Alphen aan den Rijn, NL;

Viki Bockstal, Borgerhout, BE;

Markus Kalla, Penzberg, DE;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61P 31/18 (2006.01); A61P 37/04 (2006.01); A61K 39/21 (2006.01); A61K 39/12 (2006.01); A61K 35/761 (2015.01); C12N 15/86 (2006.01);
U.S. Cl.
CPC ...
A61K 39/12 (2013.01); A61P 31/18 (2018.01); C12N 15/86 (2013.01); C07K 2319/00 (2013.01); C12N 2710/24043 (2013.01); C12N 2740/16134 (2013.01); C12N 2740/16234 (2013.01); C12N 2740/16334 (2013.01);
Abstract

Poxvirus vectors encoding a synthetic HIV envelope antigen and other HIV antigens, as well as compositions containing such poxvirus vectors and uses of such poxvirus vectors as vaccines to provide improved immunity against HIV, are provided. Also provided are vaccine combinations containing the disclosed poxvirus vectors, adenovirus vectors encoding one or more HIV antigens, and one or more isolated HIV antigenic polypeptides, and methods of using the vaccine combinations to provide improved immunity against HIV.


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