The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 15, 2023
Filed:
May. 04, 2017
Applicant:
Fred Hutchinson Cancer Center, Seattle, WA (US);
Inventors:
Stanley R. Riddell, Sammamish, WA (US);
Joshua Veatch, Seattle, WA (US);
Assignee:
Fred Hutchinson Cancer Center, Seattle, WA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 63/00 (2020.01); C12N 15/85 (2006.01); C07H 21/04 (2006.01); A61K 39/00 (2006.01); A61K 35/17 (2015.01); A61P 31/12 (2006.01); A61P 37/06 (2006.01); A61P 35/02 (2006.01); A61P 31/04 (2006.01); A61K 39/39 (2006.01); C07K 14/255 (2006.01); C07K 14/535 (2006.01); C07K 14/54 (2006.01); C12N 15/86 (2006.01);
U.S. Cl.
CPC ...
A61K 39/0011 (2013.01); A61K 35/17 (2013.01); A61K 39/39 (2013.01); A61P 31/04 (2018.01); A61P 31/12 (2018.01); A61P 35/02 (2018.01); A61P 37/06 (2018.01); C07K 14/255 (2013.01); C07K 14/535 (2013.01); C07K 14/5434 (2013.01); A61K 2039/5154 (2013.01); A61K 2039/5156 (2013.01); A61K 2039/5158 (2013.01); A61K 2039/55522 (2013.01); A61K 2039/55533 (2013.01); A61K 2039/55538 (2013.01); C07H 21/04 (2013.01); C12N 15/85 (2013.01); C12N 15/86 (2013.01); C12N 2510/00 (2013.01); Y02A 50/30 (2018.01);
Abstract
The present disclosure relates to immune cells that express an exogenous neoantigen and an immunogenicity enhancer, or to T cells that express an exogenous neoantigen, and their use in treating a disease or disorder, such as cancer for tumor associated neoantigens. Related expression constructs, kits, host cells, pharmaceutical compositions, and methods are also provided.