The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 15, 2023
Filed:
May. 17, 2021
Applicants:
California Institute of Technology, Pasadena, CA (US);
Indi Molecular, Inc., Culver City, CA (US);
Inventors:
Blake Farrow, Pasadena, CA (US);
James R. Heath, South Pasadena, CA (US);
Heather Dawn Agnew, Culver City, CA (US);
Assignees:
INDI MOLECULAR, INC., Culver City, CA (US);
CALIFORNIA INSTITUTE OF TECHNOLOGY, Pasadena, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); C07B 59/00 (2006.01); A61K 38/12 (2006.01); A61K 38/06 (2006.01); C07K 7/52 (2006.01); C07K 5/083 (2006.01); A61K 38/08 (2019.01); C07K 7/06 (2006.01); G01N 33/531 (2006.01); A61K 47/60 (2017.01); C07K 7/08 (2006.01); G16B 5/00 (2019.01);
U.S. Cl.
CPC ...
A61K 38/005 (2013.01); A61K 38/06 (2013.01); A61K 38/08 (2013.01); A61K 38/12 (2013.01); A61K 47/60 (2017.08); C07B 59/008 (2013.01); C07K 5/0808 (2013.01); C07K 7/06 (2013.01); C07K 7/08 (2013.01); C07K 7/52 (2013.01); G01N 33/531 (2013.01); A61K 38/00 (2013.01); C07B 2200/05 (2013.01); C07K 2319/01 (2013.01); C07K 2319/70 (2013.01); G01N 2333/33 (2013.01); G16B 5/00 (2019.02); Y02A 50/30 (2018.01);
Abstract
The present application provides stable peptide-based Botulinum neurotoxin (BoNT) serotype A capture agents and methods of use as detection and diagnosis agents and in the treatment of diseases and disorders. The application further provides methods of manufacturing BoNT serotype A capture agents using iterative on-bead in situ click chemistry.