The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 15, 2023

Filed:

Feb. 23, 2018
Applicant:

The Cleveland Clinic Foundation, Cleveland, OH (US);

Inventors:

Jaroslaw Maciejewski, Beachwood, OH (US);

Sergei Vatolin, Bay Village, OH (US);

Assignee:

THE CLEVELAND CLINIC FOUNDATION, Cleveland, OH (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/513 (2006.01); A61K 31/136 (2006.01);
U.S. Cl.
CPC ...
A61K 31/513 (2013.01); A61K 31/136 (2013.01);
Abstract

Anti-aging compounds identified using the lead compounds violuric acid and 1-naphthoquinone-2-monoxime are described. The compounds are redox catalysts that appear to improve the function of hematopoietic stem cells. The compounds can be used to decrease the rate of aging in a subject, or to treat or decrease the risk of developing an age-related disease or disorder.


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