The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 08, 2023
Filed:
Jan. 15, 2019
Merative Us L.p., Ann Arbor, MI (US);
Cheryl L. Eifert, Watertown, MA (US);
Jia Xu, Somerville, MA (US);
Claudia S Huettner, Jamaica Plain, MA (US);
Fang Wang, Plano, TX (US);
Vanessa Michelini, Boca Raton, FL (US);
Elinor Dehan, Haniel, IL;
MERATIVE US L.P., Ann Arbor, MI (US);
Abstract
Computer based methods, systems, and computer readable media for intelligently accessing various types of pharmaceutical information in a content repository and ranking drugs at the variant level, gene level, and pathway level. In some cases, drugs that target the same gene, gene variant, or biological pathway may be ranked based upon in vitro, pre-clinical, clinical, or post-clinical evidence. To determine ranking of a plurality of drugs, information pertaining to drug administration is analyzed for the drugs. For a plurality of drugs, attributes corresponding to the drug are determined, wherein the attributes include a variant or a gene targeted by the drug, and a biological pathway comprising the targeted variant or gene. The plurality of drugs are ranked according to a drug effectiveness score based on one or more of a determined efficacy, potency, or toxicity.