The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 08, 2023

Filed:

Mar. 27, 2018
Applicants:

NH Foods Ltd., Osaka, JP;

National Agriculture and Foods Research Organization, Tsukuba, JP;

Inventors:

Eri Takeuchi, Tsukuba, JP;

Kana Urayama, Tsukuba, JP;

Takashi Matsumoto, Tsukuba, JP;

Kazuki Morioka, Tsukuba, JP;

Makoto Yamakawa, Tsukuba, JP;

Kazuo Yoshida, Tsukuba, JP;

Toru Kanno, Tsukuba, JP;

Katsuhiko Fukai, Tsukuba, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/569 (2006.01); G01N 1/28 (2006.01);
U.S. Cl.
CPC ...
G01N 33/569 (2013.01); G01N 33/56911 (2013.01); G01N 33/56983 (2013.01); G01N 1/28 (2013.01); G01N 2800/26 (2013.01);
Abstract

The purpose of the present invention is to: provide an agent that effectively suppresses inhibition of antigen-antibody reaction in an immunoassay using a sample containing a body fluid, in particular, a component derived from a biological mucosal membrane, such as saliva; and to suppress false positive and false negative results in the immunoassay. The present invention provides an agent for suppressing inhibition of immune reaction, characterized in that the agent comprises a compound of the following (1) or (2): (1) Sulfonic acid compound of the formula R—SOH or a salt thereof. (In the formula, Ris selected from the group consisting of: a straight-chain C-Calkyl group; a straight-chain C-Calkyl group substituted with an aryl group having at least one straight-chain C-Calkyl group; and an aryl group having at least one straight-chain C-Calkyl group. These groups may include a substituent group); and (2) Quaternary ammonium ion of the formula N—RRRRor a salt thereof. (In the formula, R—Rare each independently a straight-chain C-Calkyl group, or an aryl group substituted with at least one straight-chain C-Calkyl group. These groups may include a substituent group); wherein the agent is capable of suppressing immune reaction inhibitory action caused by a body fluid in an immunoassay sample.


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