The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 08, 2023

Filed:

Jan. 23, 2022
Applicant:

S2 Genomics, Inc., Livermore, CA (US);

Inventors:

Stevan Bogdan Jovanovich, Livermore, CA (US);

Frank Zaugg, Redwood City, CA (US);

Kaiwan Chear, Livermore, CA (US);

Roger McIntosh, San Ramon, CA (US);

Nathan Pereira, Pleasanton, CA (US);

Assignee:

S2 GENOMICS, INC., Livermore, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 1/31 (2006.01); C12M 1/00 (2006.01); C12Q 1/6851 (2018.01); C12N 1/06 (2006.01); C12N 15/10 (2006.01); G01N 1/28 (2006.01);
U.S. Cl.
CPC ...
G01N 1/31 (2013.01); C12M 47/04 (2013.01); C12M 47/06 (2013.01); C12N 1/06 (2013.01); C12N 1/066 (2013.01); C12N 15/1003 (2013.01); C12Q 1/6851 (2013.01); G01N 1/286 (2013.01); G01N 2001/2866 (2013.01);
Abstract

This disclosure provides methods for producing a sample of subcellular organelles, particularly nuclei, from a tissue. In some embodiments, this disclosure provides a method of processing a tissue sample involves performing enzymatic/chemical disruption of tissue in a chamber to produce disrupted tissue comprising released cells and/or nuclei and debris; separating the released cells and/or nuclei from the debris therein; and moving the released cells and/or nuclei. In some instances, the method comprises mechanical disruption of the tissue sample.


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