The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 08, 2023
Filed:
Jul. 07, 2020
Applicant:
Rnaissance Ag Llc, Shawnee Mission, KS (US);
Inventors:
John L. Killmer, St. Louis, MO (US);
Patrick D. McLaughlin, St. Louis, MO (US);
Juan Pedro Humberto Arhancet, St. Louis, MO (US);
Assignee:
Other;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); C12N 15/11 (2006.01); C07K 14/005 (2006.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); C07K 14/005 (2013.01); C12N 15/111 (2013.01); C12N 2310/14 (2013.01); C12N 2330/50 (2013.01); C12N 2795/18122 (2013.01);
Abstract
The invention provides methods and compositions for improved production of large quantities of unencapsidated double strand RNA (dsRNA) in vivo. The disclosed methods and compositions, comprising co-expression of genes encoding orotate phosporibosyl transferase, bacteriophage coat protein and dsRNA produce a significant improvement over current in vivo methods of producing unencapsidated dsRNA.