The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 08, 2023

Filed:

Apr. 19, 2018
Applicant:

Keio University, Tokyo, JP;

Inventors:

Makoto Ishii, Tokyo, JP;

Tomoko Betsuyaku, Tokyo, JP;

Minoru Ko, Tokyo, JP;

Masaki Ieda, Tokyo, JP;

Masaya Yotsukura, Tokyo, JP;

Hisao Asamura, Tokyo, JP;

Ahmed Hegab, Tokyo, JP;

Yuhki Nakatake, Tokyo, JP;

Mayumi Oda, Tokyo, JP;

Assignee:

KEIO UNIVERSITY, Tokyo, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/02 (2006.01); C12N 15/79 (2006.01); C12N 15/63 (2006.01); C07H 21/04 (2006.01); C12N 5/071 (2010.01); A61P 11/00 (2006.01); A61P 31/16 (2006.01); A61K 35/42 (2015.01); C12N 15/86 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0688 (2013.01); A61K 35/42 (2013.01); A61P 11/00 (2018.01); A61P 31/16 (2018.01); C12N 15/86 (2013.01); C12N 2501/10 (2013.01); C12N 2501/999 (2013.01); C12N 2510/00 (2013.01); C12N 2513/00 (2013.01); C12N 2740/10043 (2013.01);
Abstract

A reagent for differentiating somatic cells into alveolar epithelial cells includes an NK2 homeobox family gene expression vector, and a Fox family gene expression vector, a method for manufacturing alveolar epithelial cells, the method including forcing a somatic cell to express an NK2 homeobox family gene and a Fox family gene and culturing the somatic cell after forced expression, an alveolar epithelial cell manufactured by the manufacturing method, and a cell medicine including the alveolar epithelial cell.


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