The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 08, 2023

Filed:

Aug. 10, 2022
Applicant:

Agenus Inc., Lexington, MA (US);

Inventors:

Dhan Sidhartha Chand, Lexington, MA (US);

Zahra Jawad, Lexington, MA (US);

Olga Ignatovich, Lexington, MA (US);

Nicola Anne Ramsay, Lexington, MA (US);

Spencer Campbell, Lexington, MA (US);

Beth Wensley, Lexington, MA (US);

Emmanuel Cyrille Pascal Briend, Lexington, MA (US);

K. Mark Bushell, Lexington, MA (US);

Benjamin Maxime Morin, Lexington, MA (US);

Veronica Franciszka Ilkow, Lexington, MA (US);

Assignee:

AGENUS INC., Lexington, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/30 (2006.01); C07K 16/28 (2006.01); A61P 35/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2803 (2013.01); A61P 35/00 (2018.01); A61K 2039/505 (2013.01); C07K 2317/31 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01);
Abstract

The instant disclosure provides multispecific molecules that specifically bind to CD96 (e.g., human CD96) and/or TIGIT (e.g., human TIGIT) and isolated antibodies that specifically bind to TIGIT (e.g., human TIGIT). Also provided are pharmaceutical compositions comprising these multispecific molecules and antibodies, nucleic acids encoding these multispecific molecules and antibodies, expression vectors and host cells for making these multispecific molecules and antibodies, and methods of treating a subject using these multispecific molecules and antibodies.


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