The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 08, 2023
Filed:
Jun. 04, 2021
Applicant:
Xencor, Inc., Monrovia, CA (US);
Inventors:
Gregory Moore, Arcadia, CA (US);
Matthew Bernett, Monrovia, CA (US);
Rumana Rashid, Arcadia, CA (US);
John Desjarlais, Pasadena, CA (US);
Assignee:
Xencor, Inc., Pasadena, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07K 1/18 (2006.01); C07K 16/28 (2006.01); C07K 16/46 (2006.01); C07K 16/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2803 (2013.01); C07K 1/18 (2013.01); C07K 16/00 (2013.01); C07K 16/2809 (2013.01); C07K 16/468 (2013.01); C07K 2317/31 (2013.01); C07K 2317/55 (2013.01); C07K 2317/565 (2013.01); C07K 2317/62 (2013.01); C07K 2317/622 (2013.01); C07K 2317/64 (2013.01); C07K 2317/94 (2013.01);
Abstract
The present invention is directed to optimized anti-CD3 variable sequences for use in a variety of bispecific formats, including those that utilize scFv components. The invention further relates to nucleic acids encoding for the polypeptide, to vectors comprising the same and to host cells comprising the vector. In another aspect, the invention provides for a pharmaceutical composition comprising the mentioned polypeptide and medical uses of the polypeptide.