The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 08, 2023

Filed:

Aug. 28, 2018
Applicant:

The Trustees of Columbia University IN the City of New York, New York, NY (US);

Inventors:

Siddhartha Mukherjee, New York, NY (US);

Abdullah Mahmood Ali, New York, NY (US);

Florence Borot, New York, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/705 (2006.01); A61P 35/00 (2006.01); C07K 16/28 (2006.01); C07K 16/30 (2006.01); A61K 39/00 (2006.01); C12N 5/0789 (2010.01); A61K 35/12 (2015.01);
U.S. Cl.
CPC ...
C07K 14/70596 (2013.01); A61K 39/0011 (2013.01); A61K 39/001111 (2018.08); A61P 35/00 (2018.01); C07K 14/70578 (2013.01); C07K 16/2809 (2013.01); C07K 16/30 (2013.01); C12N 5/0647 (2013.01); A61K 2035/124 (2013.01); C07K 2317/24 (2013.01); C07K 2317/53 (2013.01); C07K 2319/02 (2013.01); C07K 2319/03 (2013.01); C07K 2319/09 (2013.01); C07K 2319/33 (2013.01);
Abstract

Disclosed herein are compositions and methods relating to agents that target a lineage-specific cell-surface antigen and a population of hematopoietic cells that are deficient in the lineage-specific cell-surface antigen for immunotherapy of hematological malignancies.


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